Network on Chip Security - This paper designs a network security protection system based on artificial intelligence technology from two aspects of hardware and software. The system can simultaneously collect Internet public data and secret-related data inside the unit, and encrypt it through the TCM chip solidified in the hardware to ensure that only designated machines can read secret-related materials. The data edgecloud collaborative acquisition architecture based on chip encryption can realize the cross-network transmission of confidential data. At the same time, this paper proposes an edge-cloud collaborative information security protection method for industrial control systems by combining endaddress hopping and load balancing algorithms. Finally, using WinCC, Unity3D, MySQL and other development environments comprehensively, the feasibility and effectiveness of the system are verified by experiments.