The problem of information privacy has grown more significant in terms of data storage and communication in the 21st century due to the technological explosion during which information has become a highly important strategic resource. The idea of employing DNA cryptography has been highlighted as a potential technology that offers fresh hope for unbreakable algorithms since standard cryptosystems are becoming susceptible to assaults. Due to biological DNA s outstanding energy efficiency, enormous storage capacity, and extensive parallelism, a new branch of cryptography based on DNA computing is developing. There is still more study to be done since this discipline is still in its infancy. This work proposes a DNA encryption strategy based on cryptographic key generation techniques and chaotic diffusion operation.