Intellectual Property Security - In order to meet the needs of intellectual property protection and controlled sharing of scientific research sensitive data, a mechanism is proposed for security protection throughout “transfer, store and use” process of sensitive data which based on blockchain. This blockchain bottom layer security is reinforced. First, the encryption algorithm used is replaced by the national secret algorithm and the smart contract is encapsulated as API at the gateway level. Signature validation is performed when the API is used to prevent illegal access. Then the whole process of data up-chain, storage and down-chain is encrypted, and a mechanism of data structure query and data query condition construction based on blockchain smart is provided to ensure that the data is “usable and invisible”. Finally, data access control is ensured through role-based and hierarchical protection, and the blockchain base developed has good extensibility, which can meet the requirement of sensitive data security protection in scientific research filed and has broad application prospects.